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December 19, 2008
By: Tim Wright
Editor-in-Chief, Contract Pharma
Oncothyreon Inc. has announced plans to restructure and focus on development of two compounds, PX-478 and PX-866. PX-478 is an inhibitor of hypoxia inducible factor-1 alpha that is currently in a Phase I trial for advanced metastatic cancer and lymphoma. PX-866 is an inhibitor of PI-3 kinase that is also in a Phase I trial in patients with advanced cancer. The company will reduce the size of its workforce and its senior management team. Approximately eight employees in its Edmonton facility, ...
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